Is Skin Ageing Reversible? What Experts Say About the New Generation of Aesthetic Treatments

We’ve all had that moment when we look in the mirror and think, “Why does my skin look so tired?” Fine lines, dullness, and loss of firmness remind us that time is passing.

For years, the skincare industry has offered products that promise to reverse the signs of ageing. However, many are just fancy moisturisers.

A new trend in regenerative aesthetic treatments in the UK is shifting the focus from prevention to the actual reversal of ageing signs.

So, is reversing skin ageing actually possible or just a marketing myth? We asked the experts, and according to the team at Health and Aesthetics, a medically led UK clinic specialising in regenerative treatments, the answer lies in understanding how the skin repairs itself. “Treatments like exosomes and polynucleotides do not just plump the surface. They work at a cellular level to stimulate collagen, repair tissue, and restore elasticity. That is where real, long-term rejuvenation begins.”

Let’s explore what this means and whether these evidence-based therapies can help revive your skin.

Exosomes: The Tiny Messengers That Help Skin Heal

As we age, it’s normal for our skin to change. As time passes, our bodies produce less collagen, resulting in weaker and less elastic skin. You might notice:

• Fine lines and wrinkles
• Thinner, more fragile skin
• Dull skin with uneven colour
• Slower healing of cuts and wounds

Regenerative therapies don’t just hide these changes. They work to activate your skin’s natural abilities and restore what ageing has taken away.

Exosomes are tiny messengers that our cells naturally release. They help with healing and renewing tissues.

In beauty treatments, we can use exosomes either on the skin’s surface or by injecting them into the skin.

Their benefits include the following:

• Boosting collagen and elastin production
• Reducing inflammation
• Improving moisture and skin texture
• Helping recovery after procedures like microneedling

Exosomes are exciting because they do more than treat symptoms; they help your skin work better from within.

Did you know? Exosomes are used in medicine for healing wounds and promoting hair growth.

What Are Polynucleotides and DNA Repair?

Polynucleotides are a type of treatment that, although hard to pronounce, is easy to understand. These injectable therapies utilise small pieces of DNA, often derived from salmon, to aid in skin healing and regeneration.

Here’s what they can do:

• Increase skin moisture
• Improve skin elasticity and firmness
• Reduce redness and fine lines
• Strengthen the skin barrier

These treatments work well on sensitive or damaged skin, especially around the eyes and lips. The results improve gradually with each session.

A recent study from Wiley Online Library showed that polynucleotide therapies significantly improved skin firmness and moisture after just three sessions.

Biostimulators vs Botox: What’s the Difference

Here’s how you can differentiate biostimulators and botox through this table:

Feature	Biostimulators	Botox
How It Works	Stimulates natural collagen production	Temporarily relaxes targeted muscles
Best For	Volume loss, skin laxity, long-term rejuvenation	Dynamic wrinkles
Results Timeline	Gradual (over 3-6 months)	Quick (within 3-7 days)
Longevity	Long-lasting (up to 2 years)	Typically lasts 3-6 months
Pros	Natural-looking results, boost skin thickness	Immediate wrinkle reduction, quick procedure
Cons	Slower to show results, not for deep expression lines	Temporary results, needs regular top-ups
Downtime	Moderate	Minimal to none
Ideal User	Those seeking long-term improvement and volume	Those wanting quick fixes for lines and wrinkles

What the Experts Recommend

What therapy is right for you? The NHS states that safety and the skills of practitioners must take priority for any non-surgical cosmetic procedures.

Dr. Karen Doherty, an aesthetic expert in London, explains that “regenerative injectables like exosomes and polynucleotides can improve different skin layers and help increase collagen production when used together.”

Experts suggest you consider the following:

• The current condition of your skin.
• How much downtime can you manage?
• Your age, lifestyle, and budget.

Simple Comparison Treatment Chart

Here’s a quick but simple comparison treatment chart to check:

Treatment	Main Benefit	Results Timeline	Downtime	Longevity
Exosomes	Collagen and healing	2-4 weeks	Minimal	Builds over time
Polynucleotides	Hydration and repair	2-6 weeks	Minimal	Lasts several months
Biostimulators	Volume and firmness	3-6 months	Moderate	Up to 2 years
Botox	Wrinkle smoothing	3-7 days	Low	3-6 months

How to Choose What’s Right for You?

The best way to rejuvenate your skin is to understand what your skin needs and choose treatments that work for you, rather than trying the latest trend.

This might mean using polynucleotides alone for a big event. Alternatively, it could involve a combination of exosomes and biostimulators, guided by a skilled professional.

Look for:

• Healthcare specialists who are trained
• Places that offer consultations and patch testing
• Realistic timelines and expectations

Most importantly, steer clear of any treatment that promises “instant miraculous results.” Healthy skin takes time, not a quick fix.

Conclusion

We can’t fully stop skin ageing, but we can reduce its visible effects and even reverse some signs. Treatments like exosomes, polynucleotides, and biostimulators offer real improvements, going beyond just surface fixes to truly renew your skin’s look and feel.

If your skincare products aren’t working, it might be time to explore other options. With science-based, expert-led treatments, getting healthier, firmer, and younger-looking skin could be easier than you think.

To find out which treatment is right for you, talk to a qualified expert and look at your options.